Saul of Tarsus was a powerful enemy of Christian. No one could witness to him. He was full of hate. He persecuted Christians, but he met Jesus on the Road to Damascus and became one of the greatest proponents for Christianity who ever lived.
The Lord hears our requests when we ask, seek, and knock not because we are so good, but because of our persistence in prayer, "I say to you, though he will not rise and give to him because he is his friend, yet because of his persistence he will rise and give him as many as he needs (Luke 11:8). Never doubt that God is able to do exceeding, abundantly more than we can ask or think according to the power that is at work within us (Ephesians 3:20).
Do NOT think your prayers are weak or ineffective for the five people who are hard to reach or who may have rejected Jesus Christ. If they are hard, you "go hard" in your prayer life! Ask, seek, and knock are really three different ways of doing the same thing. In order words, you should ask, and ask, and keep on asking in prayer. Now give yourself the highest of fives, a list of five people you are constantly praying for. Friends don't let friends miss heaven! So, intercede to high heaven for your five people to be saved or reconnected to Jesus Christ today! Don't give up on them because God didn't give up on us! Jesus died and rose again while we were yet sinners that we might have relationship with God, an abundant life here on earth, and eternal life in heaven. There is power in prayer! The prayers of the righteous availeth much!!